DAO 127:225-230 (2018) - DOI: https://doi.org/10.3354/dao03204
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Multicentric plasmacytoma in a harbor porpoise Phocoena phocoena off the coast of Whidbey Island, Washington State, USA
Barry H. Rickman1,2,3,*, Tim Morgan4, Matthew Klope2, Susan Berta2, Sandra Dubpernell2, Howard Garrett2, Mary Jo Adams2, Stephanie A. Norman2,5
ABSTRACT: Necropsy of a female adult pregnant harbor porpoise Phocoena phocoena revealed a multicentric plasmacytoma. The plasmacytoma infiltrated the cranial lung lobes, mediastinal lymph nodes and the spleen. Diagnosis was based on gross, histopathologic and immunohistochemical studies. Histopathology revealed a diffuse proliferation of atypical pleomorphic neoplastic round cells with plasmacytic features. Positive immunohistochemistry with anti-CD79a and anti-CD20 antibody markers and anti-multiple myeloma oncogene 1 (MUM-1) for plasmacytoma confirmed this neoplasm to be of B-cell origin. This is the first recorded case of a plasmacytoma in a harbor porpoise. Routine viral screening was negative via standard PCR for herpesvirus and reverse transcriptase PCR for morbillivirus. Retroviral screening was not performed.
KEY WORDS: Cancer · Neoplasia · Cetacean · Harbor porpoise · Multicentric anaplasmic plasmacytoma · Phocoena phocoena · Marine mammal
| Full text in pdf format | Cite this article as: Rickman BH, Morgan T, Klope M, Berta S and others (2018) Multicentric plasmacytoma in a harbor porpoise Phocoena phocoena off the coast of Whidbey Island, Washington State, USA. Dis Aquat Org 127:225-230. https://doi.org/10.3354/dao03204
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