DAO 56:195-200 (2003)  -  doi:10.3354/dao056195

ABSTRACT: The present work provides the first information concerning the immunostimulatory activity of trout interleukin (IL)-1β-derived peptides in vivo. Previous studies have demonstrated the ability of 2 such peptides, referred to as P1 and P3, to up-regulate a range of important immune parameters in vitro. P1 corresponds to fragment 146-157 (YVTPVPIETEAR) of the trout sequence and is analogous to a biologically active mammalian IL-1

KEY WORDS: Interleukin-1β · Phagocytosis · Respiratory burst · Disease resistance · Immunomodulation · VHS